I. Sumo
Phosphholikids ikirasi yeLipdid izvo zvakakosha zvikamu zvemitambo yemasero uye uve nechimiro chakasarudzika chinosanganisira iyo hydrophilic musoro uye hydrophobic miswe. Iyo ampipathic yemhando ye phosphholiclipds inovatendera kuti vaite lipid bilay bilayers, iyo iri hwaro hwemasero membranes. Phospholhilipds inoumbwa nejlycrol backbone, maviri mafuta acid ketani, uye boka re phosphate, nemapoka akasiyana-siyana emativi akasungirirwa phosphate. Ichi chimiro chinopa phospholiclipsics yekuzvivanza kuti ibudise muLipid Bilayers uye vesicles, izvo zvakakosha zvekuvimbika uye kushanda kwemabhiragi ezvinyorwa.
Phospholhilipsids anotamba chinzvimbo chakakosha mumasango akasiyana siyana nekuda kwezvakaringana zvivakwa, kusanganisira emulsization, solubilization, uye kusimbisa mhedzisiro. Muindasitiri yechikafu, phospholhilips anoshandiswa se emlsifiers uye stabilizers mune yakagadziriswa chikafu, pamwe neyekuchenesa zvinhu nekuda kwezvikonzero zvavo zvekugona. Mune cosmetics, phospholiclics inoshandiswa kune yavo yekuisa uye inonyorovesa zvivakwa, uye nekuvandudza kutakura kwezvinhu zvinoshanda muzvinyorwa zveganda uye zvigadzirwa zvemunhu zvega. Pamusoro pezvo, phospholhilics ine zvakakosha zvekushandisa mumishonga, kunyanya mune zvinodhaka zvekushandisa uye kuumbwa, nekuda kwekukwanisa kwavo kwekutarisa uye kuendesa zvinodhaka kune chaiyo tarisiro mumuviri.
Ii. Basa rePhosphholiclics muChikafu
A. Emulesificization uye Stabilizing Progres
Phospholhilipds anoshanda se emulsifiers akakosha muindasitiri yechikafu nekuda kwechimiro chavo cheAmpiphilic. Izvi zvinovatendera kuti vabatane nemvura uye nemafuta, kuita kuti vabudirire pakudzima emulsions, senge mayoneka, macalad nguo, uye zvigadzirwa zvakasiyana-siyana zvemukaka. Iyo hydrophic musoro we phosphholid molepuli inokwezva nemvura, nepo hydrophobic miswe yakadzokororwa nazvo, zvichikonzera kuumbwa kwenzvimbo yakagadzikana pakati peoiri nemvura. Iyi pfuma inobatsira kudzivirira kupatsanurana uye kuchengetedza yunifomu yekugovera kwezvinhu zvigadzirwa zvekudya.
B. Shandisa mukugadzira chikafu uye kugadzirwa
Phospholiclics anoshandiswa pakugadziriswa kwechikafu kune yavo inoshanda zvinhu, kusanganisira kugona kwavo kugadzirisa zvinyorwa, kuvandudza viscosity, uye kupa kugadzikana kune zvigadzirwa zvekudya. Ivo vanowanzo shandiswa mukugadzirwa kwezvinhu zvakabikwa, kushingirira, uye zvigadzirwa zvemukaka zvekusimudzira kunaka uye mararamiro ehupenyu hwekupedzisira. Pamusoro pezvo, phospholiclics inoshandiswa seanonamira-inonamira-inonamira mumiriri mukugadziriswa kwenyama, huku, uye zvigadzirwa zvegungwa.
C. Hutano Hutano uye Kubatsira Kwekuvaka
Phospholiclics inopa mhando yemhando yekudya kwemari yematunhu echisikigo ezvakawanda zvekudya, senge mazai, soya, uye zvigadzirwa zvemukaka. Ivo vanozivikanwa nekuda kwavo kugona kwavo hutano, kusanganisira basa ravo muchikwereti uye basa, pamwe nekugona kwavo kutsigira hutano hwehuropi uye basa rekuziva. Phospholicikids inofananidzwawo mukana wavo wekuvandudza lipdud metabolism uye Cardiovascular Hutano.
III. Zvikumbiro zve phospholiclics mune cosmetics
A. EMULSINGING uye moisturizing mhedzisiro
Phospholikids inoshandiswa zvakanyanya mune cosmetics uye zvigadzirwa zvega zvekutarisira kuti zvive zvakanaka uye zvinyoro-nyoro mhedzisiro. Nekuda kwechimiro chavo cheAmphiphilic, phospholiclics anokwanisa kugadzira emulsions akasarudzika, achibvumira mvura nemafuta-zvakavakirwa-zvakakonzerwa nemakiromita uye marara ane mitsara yakatsiga, yunifomu. Uye zvakare, iyo yakasarudzika yemhando ye phospholiclics inovabatsira kutevedzera ganda remagetsi remagetsi uye kudzivirira kurasikirwa kwemvura, izvo zvinobatsira pakuchengetedza hydration uye kudzivirira kuoma.
Phospholiclicids senge lacithin yakashandiswa se emlsifiers uye moisturizers mune dzakasiyana siyana dzeCosmetic uye ganda rezvigadzirwa, kusanganisira maCreams, lotions, uye sunscors. Kugona kwavo kuvandudza chimiro, kunzwa, uye zvinyoro-nyoro kwezvigadzirwa izvi kunovaita zvinokosha zvirimo mumatare eCosmetic.
B. Kuwedzeredza kuendesa kwekushanda zvinwiwa zvinoshanda
Phospholhilipsids anotamba basa rakakosha mukuvandudza kutumirwa kwezvinhu zvinoshanda mumakambani eCosmetic uye kweganda. Kugona kwavo kuumba lapossomes, vesicles kwakaumbirwa ne phonphholid bilayers, inobvumira kuti ishandiswe uye dziviriro yemazita anoshanda, akadai seVitamins, antioxidants, uye zvimwe zvinobatsira. Kuvandudzwa uku kunobatsira kuvandudza kugadzikana, kusaririra, uye zvakarongedzwa kuburitsa kweaya makomisheni eganda, achiwedzeredza kushanda kwavo muzvigadzirwa zveganda uye zveganda.
Uyezve, phospholilid-yakavakirwa kuburitswa mashandiro ekuti akunde matambudziko ekuendesa hydrophobic uye hydrophic inoshanda mishonga, ichiita kuti vatakure zviitiko zvakasiyana siyana zvehuwandu hwekuita cosmetic. Forosomal Fomu rine phospholiclicd yakave yakashandirwa zvakanyanya mukurwara-kukweva, zvinonyungudutsa, uye zvigadzirwa zveganda, uko kwavanogona kuendesa zvinongedzo zvinoshanda zvinobudirira kune zvinangwa zveganda ganda.
C. Basa muGandacare uye Zvigadzirwa Zvemunhu Zvemunhu
Phospholhilipsids anotamba basa rakakosha mubhuku remaginha uye ega ega, zvichikonzera kushanda kwavo uye kushanda kwavo. Pamusoro pekukuvara kwavo, Moisturizization, uye kuisirwa-kuisimudzira zvivakwa, phospholhilipsid zvakare inopa mabhenefiti akadai seganda mamiriro ezvinhu, uye kugadzirisa. Aya mamorekuru aya anogona kubatsira kuvandudza ruzivo rwese uye kuita kwezvigadzirwa zvecompetic, zvichiita kuti vafarire zvirimo mukuumbwa kweganda.
Kubatanidzwa kwe phospholiclipds mune yeganda uye zvigadzirwa zvechiratidzo zvega Chisikwa chavo chaunga chinovatendera kuti vataure zvakasiyana-siyana ganda uye vhudzi zvaunoda, kupa zvese zvinobatsira uye zvinobatsira kune vatengi kune vatengi.
Iv. Kushandiswa kwe phospholiclics mune mishonga yemishonga
A. Dhirowa Dhimoni uye kuumbwa
Phospholhilipsils anotamba basa rakakosha mubhasicucal mushonga uye kuumbwa nekuda kwechimiro chavo cheAmpiphilic. Ichi chivakwa chinogonesa phospholiclicid kuti uvandudze solubility, kugadzikana, uye kusvetuka kwemishonga isinganyorerwe, kuvandudza mukana wavo wekushandisa. PHOPSHOLIKID-yakavakirwa zvinodhaka zvinodhaka zvinogona zvakare kuchengetedza zvinodhaka kubva mukushatisa, tarisiro inosungirwa madhiri, uye tarisiro chaiyo cell kana tishu, inopa mukana wekuwedzera zvinodhaka uye zvakaderedzwa mhedzisiro.
Kugona kwema phospholilick kuumba zvivakwa zvekuzvivenga, sekuzvisimbisa uye micelle, zvakabiwa mukuvandudzwa kwemishonga yakasiyana-siyana yemishonga, kusanganisira nemuromo, mafuro emabhonzo. LIPID-yakavakirwa mafambiro, akadai secompols, solid lipid stoparticles, anowanzobatanidza phospholiclics kuti akunde zvinodhaka uye kusimuka, pakupedzisira kuvandudza zvibodzwa zvezviratidzo zvezvinyorwa zvechinangwa.
B. Liposomal Dhaka Diki Systems
System yeLiposomal inodhaka mishonga ndeye muenzaniso wakakurumbira wekuti phospholiclipds anoshandiswa sei mukushandisa mishonga yemishonga. Rusununguko, runyorwa rwe phosphholid bilayers, ana kugona kusimbisa zvinodhaka mukati memukati memukati kana liplid bilayers, kupa nharaunda inodzivirira uye kudzora kusunungurwa kwemishonga. Izvi zvinodhaka zvinodhaka zvinogona kugadziriswa kuti uvandudze kutumirwa kwemhando dzakasiyana dzemishonga, mishonga inorwisa chemo
Iko kuwanda kwechiRipoti kunobvumira kufambiswa kwehukuru hwavo, kubhadharisa, uye zvivakwa zvemusoro kuti uwedzere kurodha zvinodhaka, kugadzikana, uye kugoverwa kwematehwe. Kuchinja uku kwakatungamira mukuvandudzwa kwemakiririri akagamuchirwa liposomal yekufungidzira kwekushanda kwakasiyana siyana, kusimbisa kukosha kwe phospholiclic
C. Zvinogona kushandiswa mukutsvaga kwekurapa uye kurapwa
Phosphholicikids inobata mukana wekushandisa mukutsvaga zvekurapa uye kurapwa kunze kwezvinhu zvinodhaka zvinodhaka. Kugona kwavo kubatirana neCell membranes uye modulate cellular maitiro anopa mikana yekukudziridza mavara ekurapa maratidziro ekurapa. PHOPSHOLIFID-yakavakirwa mafomu akaongororwa nekuda kwekugona kwavo kuronga nzira, vanomisikidza eGexy vamiriri veGene, vachireva zvinhu zvakadai seGegeni
Uyezve, phosholikids yakaongororwa basa ravo mukusimudzira maitiro ekugadzirisa uye kuumbwa, kuratidzira kugona mukuporesa maronda, mishonga yeTissue, uye mushonga wekubereka. Kugona kwavo kutevedzera masokisi mesermy membranes uye kuwirirana neBiology Systems inoita phospholiclipsids aivimbisa avenue yekufambira mberi kwekurapa uye kurapwa.
V. ZVINOKOSHA uye NEMUFANANIDZO YEMAHARA
A. Kutaurisa kufunga uye zvine chekuita nekuchengetedza
Kushandiswa kwe phospholhilipds mune chikafu, zvizoro, uye mishonga inopa inofungidzirwa zvakasiyana-siyana yekufungidzira uye zvine chekuita nekuchengetedza. Muindasitiri yechikafu, phospholhilips inowanzo shandiswa se emlsifiers, stabilizders, uye kuburitsa masisitimu ekushanda anoshanda. Mitemo yekudzora, yakadai seyakagadzirwa uye zvinodhaka Kuongororwa kwekuchengetedza kwakakosha kuti uve nechokwadi chekuti vanozvipira-vanobva phosphholid-yakavakirwa chikafu chakachengeteka pakushandisa uye kutevedzera mitemo yakasimbiswa.
MuCosmetic indasitiri, phospholiclics inoshandiswa muganda reganda, bvudzi rebvudzi, uye zvigadzirwa zvemunhu zvemukati zvemollient, moisturizization, uye ganda risingazivikanwe. Masangano ekuzvidzora, akadai seye European Union's cosmetic kutonga uye neUS Kubata uye DVDA) Kuongororwa kwekuchengetedza uye kufananidzira zvidzidzo zvinoitwa kuti uongorore nhoroondo yekuchengetedza ye phosphholid-based cosmetic organient.
Muchikamu chechikadzi, iyo yekuchengetedza uye yekuzvidzora pfungwa dzePhospholiclips inosanganisira kushandisa kwavo mudhara mune zvinodhaka, liposomal mafomu, uye mishonga yemishonga. Zviremera zvekuzvidzora, zvakadai seFDA uye European mishonga agency (Ema), ongorora kuchengeteka, uye mhando yezvigadzirwa zvemishonga zvine phosphholipvids kuburikidza neakasimba preclinical uye clinical ongorora maitiro. Iko kunetsekana kwekunetseka kwakabatana ne phospholicikids mune mishonga-mishonga inotenderera ichitenderedza kutapudza, uye kuenderana nezvinoita zvinodhaka.
B. Anobuda Mafambiro uye Ruzivo
Kushandiswa kwe phospholibids mune chikafu, zvizoro, uye mishonga mishonga iri kusangana nemaitiro uye zviitiko zvinoshamisa. Muindasitiri yechikafu, kushandiswa kwe phospholiclics se emulsifiers yemasikirwo uye masisitimu ari kuwana traction, anotyisidzirwa neyakadiwa yekuda kwegwaro rakachena uye zvisikwa zvekudya zvakasikwa. Tekinoroji inogadzira, yakadai se nanoemulsions yakasimbiswa ne phospholids, vari kuongororwa kusimudzira iyo solubility uye yekuvhara yezvikamu zvekushandisa, senge mishonga yezvinhu zvakanaka uye mavitamini.
Mune indasitiri yekuzora, kushandiswa kwe phospholiclic Zvimiro zvinosanganisira phosphholid-based nanoffrriers, senge liposoms uye nicosting lipmit vatakuri (NLCS), zvinopa kugadzirwa kwekugadzira mukugadzira mukurapa-kuchembera, kuchengetedzwa kwezuva, uye zvakasarudzika zvigadzirwa zveganda.
Mukati mechikamu chechiremba, zvinobuda muzvikamu zviri muPhosphholid-based Dishm Dishmit inosanganisira yakarongedzwa mishonga, yakatarisana nekurapa, uye kusanganisa zvinodhaka zvinodhaka. Yepamberi LIPID-based Vatakuri
C. Zvinogona kuyambuka-indasitiri kuwanda uye mikana yekuvandudza
Iko kuwanda kwe phospholhilipsid kunounza mikana yekubatana-indasitiri kubatana uye kukura kwezvinhu zvinogadzirwa nekupindirana kwekudya, zvizhinha, uye mishonga. Kuunganidzwa-maindasitiri kuunganidzwa kunogona kufambisa kuchinjanisa kwezivo, matekinoroji, uye maitiro akanakisa ane chekuita nezvokushandisa phospholicd pamapoka akasiyana. Semuenzaniso, nyanzvi mune lipid-yakavakirwa kuburitswa kubva muindasitiri yemishonga inogona kuvhenekerwa kuti uwedzere dhizaini uye kuita kweiyo lipid-based inoshanda zvinhu mune zvekudya nezvinorema.
Uyezve, kusunganidzwa kwechikafu, zino, uye mishonga, uye mishonga, uye mishonga inotungamira mukuvandudzwa kwezvinhu zvigadzirwa zvechizhinji zvinoenderana nehutano, hutano uye hunyoro. Semuenzaniso, nutrecicals uye cosmEceuticals inosanganisira phospholicids iri mumhedzisiro yekubatana-kwemaindasitiri-indasitiri mhinduro dzinokurudzira zvese zvemukati uye dzekunze hutano. Kubatana uku kunoitawo mikana yekutsvaga uye zvekutanga zvekusimudzira zvakanangana nekuongorora izvo zvinogoneka zvidzitiro uye zvinyorwa zvezvinyorwa zve phospholiced zvigadzirwa zvekugadzira.
Vi. Mhedziso
A. Repank of the wroatlity uye kukosha kwe phospholiclics
Phospholhilipsids tamba basa rakarukwa mumasango akasiyana-siyana, kupa huwandu hwakawanda hwekushandisa mune zvekudya, zvizhinha, uye zvikamu zvemishonga. Chimiro chavo chemakemikari chakasarudzika, icho chinosanganisira zvese hydrophilic uye hydrophobic matunhu, zvinoita kuti ivo vaite sechiitiko, Stabilizers, uye kuburitsa masisitimu ekushanda zvinongedzo. Muindasitiri yekudya, phospholiclics inopa kugadzikana uye kuumbwa kwezvikafu zvakagadziriswa, nepo mune cosmetics chikafu, ivo vanopa moisturics, vanonyorova, vane midziyo yekumanikidza, inovandudza midziyo yezvigadzirwa zveganda. Uyezve, iyo misheni indasitiri inowedzera phosphholicikids mune zvinodhaka zvekushanda, likemal mafungidziro, uye seyechikara yekugadzira nekuda kwekugona kwavo kusimudzira kusimudzira kusimudzira uye chinangwa chaicho nzvimbo dzekuita.
B. Zvinoregererwa kuti uwane ramangwana rekutsvaga uye maindasitiri ekushandisa
Kutsvaga kwekutsvagisa mumunda wePhosholikids kunoenderera mberi, kune zvakati wandei zvidzidzo zvenguva yemberi uye zvekushandisa maindasitiri. Chekutanga, kumwezve kutsvagisa mukuchengetedza, kushanda kwavo, uye zvinogona kugadzirwa pakati pePhospholiclics uye mimwe mishonga inokwanisa kugadzira nzira yekuvandudzwa kwechigadzirwa chechirume chinokonzeresa zvinodiwa nevatengi. Pamusoro pezvo, kuongorora kushandiswa kwe phospholikids mumapuranga ehunyanzvi senge nanoecrions Tsvagurudzo iyi inogona kutungamira kuchisikwa chezvinhu zvitsva zvigadzirwa zvinopa zvakagadziridzwa kuita uye kushanda.
Kubva pamaonero emapurikiro, kukosha kwe phospholiclics mune dzakasiyana siyana zvinoshandiswa zvinosimbisa kukosha kwekuenderera mberi kwehuwandu hwekuvandudza uye kubatana mukati uye maindasitiri. Nekuwedzera kudiwa kwezvinhu zvakasikwa uye zvinoshanda zve phospholicids mune zvekudya, zvizarisi, uye mishonga, uye mishonga inopa mukana wekuvandudza zvigadzirwa zvepamusoro, zvakaringana zvinoenderana nezvinodiwa nevatengi. Uyezve, nguva yemberi yemaindasitiri yemaindasitiri ingasanganisira kudyidzana kwechikamu, uko ruzivo uye maindasitiri kubva pakudya, maindasitiri, uye maindasitiri ezvigadzirwa zvekugadzira anopa hutano hwakanaka uye hune hutano hwakanaka.
Mukupedzisa, kuwanda kwe phospholiclics uye kukosha kwavo mune zvekudya, zvizarisi, uye mishonga, uye mishonga inovaita zvikamu zvezvigadzirwa zvakawanda zvezvigadzirwa zvakawanda. Zvavanga zvichikwanisa kutsvagisa uye nekunyorera maindasitiri ekuratidzira nzira yekuenderera mberi nekufambira mberi mune midzi yezvimisikidzwa uye mafambiro emhando, kuumba mamiriro emusika wepasi rose pamasango emadhiri.
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Kutumira Nguva: Dec-27-2023
