Nhanganyaya
Ginsenosidesikirasi yemasikirwo emakomisheni anowanikwa mumidzi yePanax ginseng chirimwa, icho chave chichishandiswa kwemazana emakore mumushonga wechinyakare weChinese. Aya ma bioactive makomisheni akawana kutariswa kwakakosha mumakore achangopfuura nekuda kwekugona kwavo hutano mabhenefiti. Muchikamu chino, tichaongorora mabhenefiti akasiyana siyana eginsenosides, kusanganisira mhedzisiro yawo pakuziva basa, immune system modulation, anti-kuzvimba zvivakwa, uye inogona kuita anticancer chiitiko.
Basa rekuziva
Imwe yeanonyanya kuzivikanwa mabhenefiti eginsenosides kugona kwavo kuvandudza kugona kwekuziva. Ongororo dzinoverengeka dzakaratidza kuti ginsenosides inogona kusimudzira ndangariro, kudzidza, uye kugona kwekuziva kuita. Migumisiro iyi inofungidzirwa kuti inopindirana nenzira dzakasiyana-siyana, kusanganisira kuchinjwa kwevaneurotransmitters, zvakadai seacetylcholine uye dopamine, uye kukurudzira neurogenesis, nzira yekugadzira neurons itsva muuropi.
Mune chidzidzo chakabudiswa mu Journal of Ethnopharmacology , vatsvakurudzi vakawana kuti ginsenosides inogona kuvandudza nzvimbo yekudzidza uye chiyeuchidzo mumakonzo nekusimudzira kutaura kweuropi-yakatorwa neurotrophic factor (BDNF), puroteni inotsigira kurarama uye kukura kwemauroni. Pamusoro pezvo, ginsenosides yakaratidzwa kudzivirira kubva kuzera-ane hukama kuderera kwekuziva uye neurodegenerative chirwere, senge Alzheimer's uye Parkinson's chirwere, nekudzikisa oxidative kusagadzikana uye kuzvimba muuropi.
Immune System Modulation
Ginsenosides yakawanikwa zvakare kugadzirisa immune system, ichiwedzera kugona kwayo kudzivirira kubva kuhutachiona nezvirwere. Mishonga iyi inoratidzwa kuti inokurudzira kugadzirwa uye kuita kwemasero ekudzivirira emuviri akasiyana, semasero anouraya echisikigo, macrophages, uye T lymphocytes, ayo anoita basa rakakosha mukudzivirira kwemuviri kubva kune hutachiona nekenza maseru.
Ongororo yakaburitswa muInternational Immunopharmacology magazine yakaratidza kuti ginsenosides inogona kusimudzira mhinduro yezvirwere mumakonzo nekuwedzera kugadzirwa kwema cytokines, ari kusaina mamorekuru anodzora immune cell kushanda. Uyezve, ginsenosides yakaratidzwa kuva ne-anti-viral uye anti-bacterial properties, zvichiita kuti ive inovimbisa mushonga wepamuviri wekutsigira hutano hwekudzivirira zvirwere uye kudzivirira kutapukira.
Anti-Inflammatory Properties
Kuzvimba kupindurwa kwechisikigo kwemasoja emuviri kukuvara uye kutapukirwa, asi kuzvimba kusingaperi kunogona kubatsira mukukura kwezvirwere zvakasiyana siyana, kusanganisira chirwere chemoyo, chirwere cheshuga, uye kenza. Ginsenosides akawanikwa aine ane simba anti-kuzvimba zvivakwa, izvo zvinogona kubatsira kudzikisira zvinokuvadza zvinokonzerwa nekuzvimba kusingaperi pamuviri.
Chidzidzo chakaburitswa muJournal yeGinseng Tsvagiridzo yakaratidza kuti ginsenosides inogona kudzvanya kugadzirwa kwepro-inflammatory cytokines uye inhibit activation yekuzvimba kusaina nzira mumasero edziviriro. Uyezve, ginsenosides yakaratidzwa kuderedza kutaura kwevarevereri vanopisa, zvakadai se cyclooxygenase-2 (COX-2) uye inducible nitric oxide synthase (iNOS), iyo inobatanidzwa mumhinduro yekuputika.
Anticancer Chiitiko
Imwe nzvimbo inofarira mukutsvaga kweginsenoside ndeye yavo inogona kuita anticancer chiitiko. Tsvakurudzo dzinoverengeka dzakaratidza kuti ginsenosides inogona kuita anti-gomarara mhedzisiro nekutadzisa kukura uye kuwanda kwemaseru egomarara, inducing apoptosis (programmed cell death), uye kudzvanya bundu angiogenesis (kuumbwa kwetsinga itsva dzeropa kutsigira bundu kukura).
Ongororo yakaburitswa muInternational Journal yeMolecular Sayenzi yakasimbisa iyo anticancer inogona yeginsenosides, kunyanya mumazamu, mapapu, chiropa, uye colorectal cancers. Ongororo iyi yakakurukura nzira dzakasiyana siyana dzinoshandisa ginsenosides mhedzisiro yavo yekurwisa cancer, kusanganisira kuchinjika kwesero kusaina nzira, kudzora kwesero kutenderera kufambira mberi, uye kukwidziridzwa kwemaitiro ekudzivirira ekurwisa cancer maseru.
Mhedziso
Mukupedzisa, ginsenosides bioactive makomisheni anowanikwa muPanax ginseng ayo anopa huwandu hwakasiyana hwehutano hunogona kubatsira. Izvi zvinosanganisira kuvandudzwa mukuziva basa, modulation ye immune system, anti-inflammatory properties, uye zvinogona kuita anticancer. Kunyange zvazvo kutsvakurudza kwakawanda kuchidiwa kuti unzwisise zvizere nzira dzekuita uye kurapa kunogona kuitika kweginsenosides, uchapupu huripo hunoratidza kuti izvi zvinosanganiswa zvinobata chivimbiso semishonga yepanyama yekusimudzira hutano hwakakwana uye kugara zvakanaka.
References
Kim, JH, & Yi, YS (2013). Ginsenoside Rg1 inodzvinyirira kushandiswa kwemasero edendritic uye T cell kuwanda mu vitro uye mu vivo. International Immunopharmacology, 17(3), 355-362.
Leung, KW, & Wong, AS (2010). Pharmacology yeginsenosides: kuongorora mabhuku. Mushonga weChinese, 5(1), 20.
Radad, K., Gille, G., Liu, L., Rausch, WD, & Kushandisa ginseng mukurapa nekusimbisa neurodegenerative kusagadzikana. Chinyorwa chePharmacological Sayenzi, 100 (3), 175-186.
Wang, Y., & Liu, J. (2010). Ginseng, inogona kuita neuroprotective zano. Evidence-Based Complementary and Alternative Medicine, 2012.
Yun, TK (2001). Sumo pfupi yePanax ginseng CA Meyer. Chinyorwa cheKorea Medical Science, 16(Suppl), S3.
Nguva yekutumira: Kubvumbi-16-2024