Nhanganyaya
Ginsenosidesimhando yemishonga yechisikigo inowanikwa mumidzi yemuti wePanax ginseng, uyo wave uchishandiswa kwemazana emakore mumishonga yechivanhu yeChina. Mishonga iyi inoshanda muhupenyu hwevanhu yakawana kutariswa kukuru mumakore achangopfuura nekuda kwekubatsira kwayo pahutano. Muchinyorwa chino, tichaongorora mabhenefiti akasiyana-siyana emishonga yeginsenosides, kusanganisira mhedzisiro yayo pakushanda kwepfungwa, kushanduka kwesimba remuviri, hunhu hwekudzivirira kuzvimba, uye kugona kurwisa kenza.
Basa rekuziva
Chimwe chezvinonyanya kuzivikanwa nezvemabhenefiti eginsenosides kugona kwawo kuvandudza mashandiro epfungwa. Ongororo dzinoverengeka dzakaratidza kuti ginsenosides inogona kusimudzira ndangariro, kudzidza, uye kushanda kwese kwepfungwa. Mhedzisiro iyi inofungidzirwa kuti inokonzerwa nenzira dzakasiyana-siyana, kusanganisira kuchinja kwema neurotransmitters, akadai seacetylcholine nedopamine, uye kukurudzira kwe neurogenesis, maitiro ekugadzira ma neuron matsva muuropi.
Muchidzidzo chakaburitswa muJournal of Ethnopharmacology, vaongorori vakaona kuti ginsenosides inogona kuvandudza kudzidza kwenzvimbo uye ndangariro mumakonzo nekuwedzera kutaura kwebrain-derived neurotrophic factor (BDNF), puroteni inotsigira kupona nekukura kwema neuron. Pamusoro pezvo, ginsenosides dzakaratidzwa kuti dzinodzivirira kubva mukuderera kwekuziva kwezera uye zvirwere zve neurodegenerative, zvakaita seAlzheimer's neParkinson's disease, nekuderedza oxidative stress uye kuzvimba muuropi.
Kuchinja Kwesimba Remuviri Wemuviri
Zvakaonekwawo kuti maginsenosides anochinja mashandiro emuviri, zvichiwedzera kugona kwawo kudzivirira kubva kuzvirwere. Izvi zvakaratidzwa kuti zvinokurudzira kugadzirwa uye kushanda kwemasero akasiyana-siyana emuviri, akadai semasero anouraya echisikigo, macrophages, uye T lymphocytes, ayo anoita basa rakakosha mukudzivirira kwemuviri kubva kuzvirwere zvinotapukira uye masero ekenza.
Ongororo yakaburitswa mumagazini yeInternational Immunopharmacology yakaratidza kuti ginsenosides inogona kuwedzera simba rekudzivirira muviri mumakonzo nekuwedzera kugadzirwa kwema cytokines, ayo ari kuratidza mamorekuru anodzora mashandiro emasero ekudzivirira muviri. Uyezve, ginsenosides dzakaratidzwa kuti dzine hunhu hwekudzivirira utachiona uye hunodzivirira mabhakitiriya, zvichiita kuti dzive mushonga wechisikigo unovimbisa wekutsigira hutano hwekudzivirira muviri uye kudzivirira hutachiona.
Zvimiro Zvinodzivirira Kuzvimba
Kuzvimba inzira yechisikigo yekudzivirira muviri pakukuvara nekutapukirwa, asi kuzvimba kwenguva refu kunogona kubatsira mukupararira kwezvirwere zvakasiyana-siyana, zvinosanganisira chirwere chemwoyo, chirwere cheshuga, nekenza. Ginsenosides dzakawanikwa dziine simba rekudzivirira kuzvimba, izvo zvinogona kubatsira kuderedza migumisiro yakaipa yekuzvimba kwenguva refu mumuviri.
Chidzidzo chakaburitswa muJournal of Ginseng Research chakaratidza kuti ginsenosides inogona kudzvinyirira kugadzirwa kwema cytokines anokonzera kuzvimba uye kudzivirira kushanda kwenzira dzezviratidzo zvekuzvimba mumasero emuviri. Pamusoro pezvo, ginsenosides dzakaratidzwa kuti dzinoderedza kutaurwa kwezvinokonzeresa kuzvimba, zvakaita se cyclooxygenase-2 (COX-2) uye inducible nitric oxide synthase (iNOS), izvo zvine chekuita nekupindura kwekuzvimba.
Basa rekurwisa kenza
Imwe nzvimbo inonyanya kufarirwa mukutsvagisa ginsenoside ndeye kugona kwavo kurwisa kenza. Zvidzidzo zvakati wandei zvakaratidza kuti ginsenosides inogona kuva nemigumisiro yekurwisa kenza nekudzivisa kukura nekuwanda kwemasero ekenza, zvichikonzera kufa kwemasero (programmed cell death), uye kudzvinyirira angiogenesis yetumor (kuumbwa kwetsinga itsva dzeropa dzinotsigira kukura kwetumor).
Ongororo yakaburitswa muInternational Journal of Molecular Sciences yakaratidza kugona kweginsenosides kurwisa kenza, kunyanya mukenza yemazamu, yemapapu, yechiropa, uye yecolorectal. Ongororo iyi yakakurukura nzira dzakasiyana-siyana dzinoshandiswa neginsenosides kurwisa kenza, kusanganisira kushandura nzira dzekutumira zviratidzo zvemasero, kudzora kufambira mberi kwemasero, uye kuwedzera kwemhinduro yekudzivirira muviri kurwisa masero ekenza.
Mhedziso
Mukupedzisa, ginsenosides imishonga inoshanda inowanikwa muPanax ginseng inopa mabhenefiti akasiyana-siyana ehutano. Izvi zvinosanganisira kuvandudzwa kwebasa repfungwa, kushandurwa kwesimba remuviri, hunhu hwekudzivirira kuzvimba, uye kugona kurwisa kenza. Kunyange hazvo kuchida kutsvagurudza kwakawanda kuti tinzwisise zvizere mashandiro ekushanda uye kugona kwekurapa kweginsenosides, humbowo huripo hunoratidza kuti mishonga iyi ine vimbiso semishonga yechisikigo yekusimudzira hutano nekugara zvakanaka.
Mareferensi
Kim, JH, & Yi, YS (2013). Ginsenoside Rg1 inodzivisa kushanda kwemasero edendritic uye kuwanda kwemasero eT mu vitro nemu vivo. International Immunopharmacology, 17(3), 355-362.
Leung, KW, & Wong, AS (2010). Pharmacology ye ginsenosides: ongororo yemabhuku. Chinese Medicine, 5(1), 20.
Radad, K., Gille, G., Liu, L., Rausch, WD, & Kushandiswa kweginseng mukurapa vachinyanya kusimbisa matambudziko etsinga. Journal of Pharmacological Sciences, 100(3), 175-186.
Wang, Y., & Liu, J. (2010). Ginseng, nzira inogona kushandiswa kudzivirira tsinga. Mushonga Unotsigirwa Neuchapupu Uye Unotsiva, 2012.
Yun, TK (2001). Kusuma kupfupi kwePanax ginseng CA Meyer. Chinyorwa cheKorea Medical Science, 16(Suppl), S3.
Nguva yekutumira: Kubvumbi-16-2024
