Corydalis Extract Tetrahydropalmatine (dl-THP)

Zita rechigadzirwa:Tetrahydropalmatine
Nhamba yeCAS:6024-85-7
Fomura yemamorekuru:C21H26NO4
Tsanangudzo:Tetrahydropalmatine ≥ 98% HPLC
Chitarisiko:Upfu hwekristaro hwakachenuruka kubva kune yero kusvika kuchena, hahunhuhwi, hunovava zvishoma
Chinhu Chikuru:Mhedzisiro yekurwadziwa kwemusoro isina kunyanya kudhakwa

Tumira email kwatiri

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Nhanganyaya yeChigadzirwa

Tetrahydropalmatine (THP), inozivikanwawo sedl-THP, Corydalin hydrochloride, kana kuti Corydalin Tube Extract, chinhu chinosanganiswa ne isoquinoline alkaloid. Chinotorwa kubva muchubhu yemushonga wekuChina weCorydalis yanhusuo. THP chinhu chisina ruvara kana cheyero yakachenuruka chine kuravira kunovava zvishoma uye chinonyunguduka che 147-149°C. Hachinyungudike mumvura asi chinonyungudika zvakanyanya mu ether, chloroform, uye ethanol. Hydrochloride ne sulfate salts zvayo zvinonyungudika mumvura.
THP yakaongororwa nezvemigumisiro yakasiyana-siyana yemishonga, kusanganisira marwadzo, marwadzo, kudzivirira tsinga, kudzivirira kuunganidzwa kweplatelet, kurwisa maronda, kurwisa bundu, uye kurwisa kupindwa muropa. Inofungidzirwa kuti ine mhedzisiro yayo yekunyaradza marwadzo nekuchinja mashandiro epakati pedopamine receptor uye yakaratidza kugona kudzivirira ma neuron kubva mukukuvara kwe ischemic. Pamusoro pezvo, THP yakaratidza mhedzisiro yekudzivirira kuunganidzwa kweplatelet uye yakaongororwa kugona kwayo kurapa maronda, kudzivirira kukura kwemasero ebundu, uye kubatsira mukupindwa muropa nezvinodhaka.
Kazhinji, Tetrahydropalmatine (dl-THP) imushonga une hunhu hwakasiyana-siyana hwemishonga uye yave ichitsvakurudzwa zvakanyanya nezvekushandiswa kwayo mukurapa. Kuti uwane rumwe ruzivo bata.grace@biowaycn.com.

Chinhu

Heano maficha eTetrahydropalmatine (THP) pamwe chete nemabhenefiti avo pahutano:
1. Hunhu hweMushonga wekurwadziwa kwemusoro:THP inoratidza mhedzisiro yekunyaradza marwadzo nekuchinja mashandiro epakati pedopamine receptor, zvichipa zororo remarwadzo pasina mukana wakakura wekupindwa muropa.
2. Migumisiro yekudzivirira tsinga:THP yakaratidza kugona kwayo kudzivirira ma neuron kubva mukukuvara kwe ischemic, kuderedza apoptosis ye neuron, uye kuderedza huwandu hwe glutamate muuropi, izvo zvinogona kubatsira mukuchengetedza kwayo neuron.
3. Kuunganidzwa kweAntiplatelet:THP yakawanikwa ichidzivirira kuungana kwemaplatelet, zvichigona kuderedza njodzi yekuumbwa kweropa rakagwamba uye zvimwe zviitiko zvine chekuita nemwoyo.
4. Rutsigiro rwehutano hwemudumbu:THP yakaratidza mhedzisiro yekurwisa maronda uye inogona kubatsira mukuderedza kuburitswa kweasidhi mudumbu, ichipa zororo kubva kumaronda emudumbu nezvimwe zvirwere zvine chekuita nazvo.
5. Kugona Kurwisa Bundu:THP yakaratidza migumisiro ye cytotoxic pamasero egomarara, zvichiratidza kuti inogona kushanda mukudzivirira kukura kwegomarara.
6. Hunhu hweKurwisa Kupindwa Muropa:THP yakaongororwa kuti inogona kuderedza zviratidzo zvekurega kushandisa opioid uye kupindwa muropa nezvinosimudzira muviri, ichipa vimbiso yekurapa kupindwa muropa nekudzivirira kudzokera kusvuta.
Zvinhu izvi zvinoratidza mabhenefiti akasiyana-siyana ehutano uye mashandisirwo angangoitwa eTetrahydropalmatine (THP) pakurapa.

Tsananguro yeChirimwa

Tetrahydropydalin (dl-THP) ndeye isoquinoline alkaloids uye ialkaloid, kunyanya iri murudzi rweCorydalis lucidum (Yan Hu Suo), asiwo mune zvimwe zvirimwa zvakaita seStephania rotunda. Zvirimwa izvi zvinoshandiswawo mumishonga yemishonga yeChinese.Corydalis chirimwa chinomera chirimwa chinogara kwenguva refu, chine hurefu hwemasendimita gumi kusvika makumi maviri, chine tuber dzakatenderera. Hunde dzacho dziri pamusoro pevhu dzakapfupika uye dzakatetepa, dzine ganda riri pamusoro pehwaro. Mashizha epasi nemashizha e cauline akafanana muchimiro, ane dzinde; mashizha e cauline anochinjana, ane mashizha maviri nematatu akasanganiswa. Shizha rechipiri rinowanzo patsanuka zvisina kukwana uye rakaita zvidimbu zvakadzika. Mashizha madiki akatetepa, akatenderera, kana kuti akatenderera. Mutsetse, anenge 2 cm kureba, ane apex yakapinza kana yakapinza uye mipendero yakanaka. Maruva ayo akaita se raceme, ane mashizha ekupedzisira kana akatarisana; mabracts akafara lanceolate; maruva akatsvuka-pepuru uye anokura akatwasuka pazvidimbu zvitete, zvinenge 6 mm kureba; calyx inodonha nekukurumidza; petals ina uye whorls dzekunze dziri 2 Zvikamu zvakakura zvishoma, nemipendero yepingi nepakati pebhuruu-pepuru. Pane chikamu chimwe chepamusoro, uye muswe unotambanuka kuita spur refu. Kureba kwespur kunoita hafu yehurefu hwese. Zvikamu zviviri zvemukati zvakatetepa pane zvekunze zviviri. Mugumo wepamusoro wakaita sebhuruu-pepuru uye wakapora, uye chikamu chezasi chine pingi; Stamens i6, uye shinda dzakabatana kuita masumbu maviri, rimwe nerimwe riine maanther matatu; ovary yakatsetseka-cylindrical, maitiro acho mapfupi uye matete, uye stigma i2, seshavishavi diki. Muchero wayo icapsule. Corydalis inonyanya kugadzirwa mumakomo kana mumasango. Nzvimbo huru dzinogadzirwa dzinosanganisira Zhejiang, Hebei, Shandong, Jiangsu, nedzimwe nzvimbo.

Tsanangudzo

Kuongorora	Tsanangudzo
Kuyedza	Tetrahydropalmatine ≥98%
Chitarisiko	Upfu hweyero yakapfava kusvika kuchena
Dota	≤0.5%
Hunyoro	≤5.0%
Mishonga yezvipembenene	Zvakaipa
Simbi dzinorema	≤10ppm
Pb	≤2.0ppm
As	≤2.0ppm
Kunhuhwirira	Hunhu
Saizi yezvimedu	100% kusvika 80 mesh
Zvisikwa zvipenyu:
Huwandu hwebhakitiriya	≤1000cfu/g
Fungi	≤100cfu/g
Salmgosella	Zvakaipa
Coli	Zvakaipa

Kushandiswa

Heano maindasitiri ekushandisa zvigadzirwa zveTetrahydropalmatine (THP):
1. Mishonga:THP inoshandiswa muindasitiri yemishonga kugadzira mishonga yekurapa marwadzo uye mishonga inodzivirira tsinga.
2. Zvinovaka Muviri:THP inoshandiswa muindasitiri yezvekudya zvine hutano kugadzira zvekudya zvinovaka muviri zvinoderedza marwadzo uye zvinotsigira hutano hwedumbu.
3. Biotechnology:THP inowana mashandisirwo mu biotechnology mukutsvagisa mukurapa kwe antiplatelet uye zvimwe zvinogona kuwedzerwa pakurapa kenza.
4. Hutano:THP inosanganiswa muzvigadzirwa zvehutano zvekurapa kupindwa muropa uye zviratidzo zvekurega zvinodhaka zvine chekuita neopioid uye kushandiswa kwemishonga inosimudzira muviri.
5. Zvishongedzo:THP inotsvakurudzwa muzvizoro kuti ione kuti ganda rinogona kugwinya uye richidzivirira kuzvimba.
Maindasitiri aya anoratidza kushandiswa kwakasiyana-siyana kweTetrahydropalmatine (THP) mukugadzirwa kwezvigadzirwa zvakasiyana-siyana uye kutsvagurudza.

Ruzivo rweKugadzira

Zvigadzirwa zvedu zvinogadzirwa uchishandisa matanho akaomarara ekudzora mhando uye zvinotevedzera mitemo yepamusoro yekugadzira. Tinonyanya kukoshesa kuchengetedzeka uye mhando yechigadzirwa chedu, tichiona kuti chinosangana nezvinodiwa nemitemo uye zvitupa zveindasitiri. Kuzvipira uku kune mhando kunovavarira kusimbisa kuvimba uye chivimbo mukuvimbika kwechigadzirwa chedu. Maitiro ese ekugadzira ndeaya anotevera:

Kurongedza uye Basa

Kuchengetera:Chengeta munzvimbo inotonhorera, yakaoma, uye yakachena, Dzivirira kubva kuhunyoro nechiedza chakananga.
Pakeji Yakawanda:20~25kg/dhiramu.
Nguva Yekutungamira:Mazuva manomwe mushure meodha yako.
Hupenyu hweSherufu:Makore maviri.
Tsananguro:Magadzirirwo akagadzirwa anogona kuwanikwa.