Methyltetrahydrofolate Calcium yakachena (5MTHF-Ca)
Methyltetrahydrofolate yakachena Calcium (5-MTHF-Ca) imhando yefolate inowanikwa zvakanyanya mumuviri uye inogona kushandiswa zviri nyore nemuviri. Imunyu wecalcium wemethyltetrahydrofolate, inova fomu inoshanda yefolate mumuviri. Folate ivhitamini B inokosha inoita basa rakakosha mumabasa akasiyana-siyana emasero, kusanganisira kugadzirwa kweDNA, kugadzirwa kwemasero matsvuku eropa, uye mashandiro etsinga.
MTHF-Ca inowanzoshandiswa sechikafu chinowedzera simba remuviri kutsigira huwandu hwe folate muvanhu vanogona kunge vachinetseka nekugaya kana kunwa folic acid yakagadzirwa inowanikwa muzvikafu zvine simba uye zvinovaka muviri. Inonyanya kubatsira vanhu vane mamwe majini akasiyana anogona kukanganisa metabolism ye folate.
Kuwedzerwa MTHF-Ca kunogona kubatsira kutsigira hutano hwese uye kugara zvakanaka, kunyanya munzvimbo dzakadai sehutano hwemwoyo, kukura kwetsinga dzetsinga panguva yekuzvitakura, mashandiro ekuziva, uye kudzora manzwiro. Zvakakosha kucherechedza kuti MTHF-Ca inofanira kushandiswa pasi pekutungamirirwa kwenyanzvi yehutano, kunyanya kune vanhu vane matambudziko chaiwo ehutano kana avo vanotora mimwe mishonga.
| Zita rechigadzirwa： | L-5-Methyltetrahydrofolate calcium |
| Mazwi anoreva zvakafanana： | 6S-5-Methyltetrahydrofolate calcium; Calcium L-5-Methyltetrahydrofolate; Levomefolate calcium |
| Fomura reMamorekuru: | C20H23CaN7O6 |
| Kurema kweMorekuru: | 497.52 |
| Nhamba yeCAS: | 151533-22-1 |
| Zviri Mukati: | ≥ 95.00% neHPLC |
| Chitarisiko: | Upfu hwekristalo huchena kusvika kune yero yakapfava |
| Nyika yakabva: | China |
| Pasuru: | 20kg/dhiramu |
| Nguva yekushanda pasherufu: | mwedzi makumi maviri nemana |
| Kuchengetera: | Chengeta munzvimbo inotonhorera uye yakaoma. |
| Zvinhu | Magadzirirwo | Mhedzisiro |
| Chitarisiko | Upfu huchena kana husina kuchena | Simbisa |
| Kuzivikanwa | Zvakanaka | Simbisa |
| Karusiyamu | 7.0%-8.5% | 8.4% |
| D-5-Methylfolate | ≤1.0 | Hazvina kuonekwa |
| Zvasara pamoto | ≤0.5% | 0.01% |
| Mvura | ≤17.0% | 13.5% |
| Kuyedza (HPLC) | 95.0%-102.0% | 99.5% |
| Dota | ≤0.1% | 0.05% |
| Simbi Inorema | ≤20 ppm | Simbisa |
| Kuwanda Kwemaplate | ≤1000cfu/g | Anokodzera |
| Mbiriso neForoma | ≤100cfu/g | Anokodzera |
| E.coil | Zvakaipa | Zvakaipa |
| Salmonella | Zvakaipa | Zvakaipa |
Kuwanikwa kwakanyanya kwehupenyu:MTHF-Ca imhando ye folate inowanikwa zvakanyanya mumuviri, zvichireva kuti inogona kunyudzwa nyore nyore nemuviri. Izvi zvakakosha nekuti vamwe vanhu vanogona kunetseka kushandura folic acid yakagadzirwa kuita chimiro chayo chinoshanda.
Chimiro chinoshanda che folate:MTHF-Ca ndiyo folate inoshanda, inozivikanwa semethyltetrahydrofolate. Iyi folate inoshandiswa zviri nyore nemuviri uye haidi mamwe maitiro ekushandura.
Munyu weCalcium:MTHF-Ca munyu wecalcium, zvinoreva kuti inobatanidzwa necalcium. Izvi zvinopa mukana wekuwedzera calcium pamwe nerutsigiro rwefolate. Calcium inokosha pahutano hwemapfupa, kushanda kwetsandanyama, kutapurirana kwetsinga, uye mamwe mabasa emuviri.
Yakakodzera vanhu vane majini akasiyana-siyana:MTHF-Ca inobatsira zvikuru kune vanhu vane mamwe majini akasiyana anogona kukanganisa metabolism ye folate. Kuchinja kwemajini uku kunogona kukanganisa kugona kwemuviri kushandura folic acid kuita chimiro chayo chinoshanda, zvichiita kuti kuwedzerwa ne active folate kuve kwakakosha.
Inotsigira zvakasiyana-siyana zvehutano:Kuwedzerwa kweMTHF-Ca kunogona kutsigira hutano hwese uye kugara zvakanaka. Kunobatsira zvikuru pahutano hwemwoyo, kukura kwetsinga dzeropa panguva yekuzvitakura, kushanda kwepfungwa, uye kugadzirisa mafungiro.
Pure Methyltetrahydrofolate Calcium (MTHF-Ca) ine mabhenefiti akawanda pahutano:
Rutsigiro rwe folate metabolism:MTHF-Ca imhando ye folate inowanikwa zvakanyanya mumuviri uye inoshanda. Inobatsira kutsigira metabolism ye folate mumuviri, iyo inokosha pakugadzirwa kweDNA, kugadzirwa kwemasero matsvuku eropa, uye kushanda kwemasero ese.
Hutano hwemwoyo:Kuwanda kwefolate kwakakosha pahutano hwemwoyo. Kuwedzerwa kweMTHF-Ca kunogona kubatsira kuderedza huwandu hwehomocysteine, amino acid iyo, kana yakakwira, inobatanidzwa nekuwedzera kwenjodzi yezvirwere zvemwoyo.
Rutsigiro rwepamuviri:MTHF-Ca inokosha panguva yekuzvitakura, sezvo ichibatsira kudzivirira zvikanganiso zve neural tube mukukura kwevana vari mudumbu. Zvinokurudzirwa kuti vakadzi vari pazera rekubereka vave nechokwadi chekuti vane folate yakakwana, kunyanya panguva yekutanga kwekuzvitakura.
Kudzora mafungiro:Folate inoita basa rakakosha mukugadzirwa kwema neurotransmitter. Kuwanda kwakakwana kwefolate kunotsigira kugadzirwa kwe serotonin, dopamine, uye norepinephrine, izvo zvakakosha pakugadzirisa mafungiro. Kuwedzera MTHF-Ca kunogona kubatsira vanhu vane matambudziko emanzwiro, akadai sekuora mwoyo.
Basa rekuziva:Folate inokosha pakushanda kwepfungwa uye hutano hwehuropi. Kuwedzerwa kweMTHF-Ca kunogona kutsigira ndangariro, kuisa pfungwa pachinhu chimwe chete, uye kushanda kwepfungwa, kunyanya muvanhu vakuru.
Rutsigiro rwezvekudya:Kuwedzerwa kweMTHF-Ca kunogona kubatsira vanhu vane kusiyana kwemajini kunokanganisa metabolism yefolate. Vanhu ava vanogona kunetseka kushandura synthetic folic acid kuita chimiro chayo chinoshanda. MTHF-Ca inopa chimiro chinoshanda chefolate zvakananga, ichidzivisa chero matambudziko ekuchinja.
Zvinovaka muviri uye zvekudya zvinovaka muviri:MTHF-Ca inowanzoshandiswa sechinhu chakakosha muzvikafu zvinovaka muviri uye zvekudya zvine hutano. Inopa mhando yefolate inowanikwa zvakanyanya mumuviri, ichipa mabhenefiti akawanda ehutano, sezvambotaurwa.
Kusimbisa chikafu nezvinwiwa:MTHF-Ca inogona kuiswa muzvigadzirwa zvekudya nezvinwiwa kuti isimbise nefolate. Izvi zvakakosha zvikuru kune zvigadzirwa zvinogutsa vanhu vane kushomeka kwefolate kana kuti vanoda folate zvakanyanya, sevakadzi vane pamuviri kana vanhu vane mamwe matambudziko ehutano.
Mishonga:MTHF-Ca inogona kushandiswa mumishonga sechinhu chinoshanda. Inogona kushandiswa mumishonga inotarisa mamiriro chaiwo ane chekuita nekushomeka kwe folate kana kusashanda zvakanaka kwe folate metabolism, senge anemia kana mamwe matambudziko emajini.
Kuzvichengeta pachako uye zvekuzora:MTHF-Ca dzimwe nguva inosanganisirwa muzvigadzirwa zvekuchengetedza muviri uye zvekuzora nekuda kwekubatsira kwayo pahutano hweganda. Folate inobatanidzwa mumabasa akasiyana-siyana emasero eganda uye inogona kubatsira pahutano hwaro hwese uye chitarisiko charo.
Chikafu chemhuka:MTHF-Ca inogonawo kuiswa muchikafu chemhuka kuti iwedzere folate kumhuka. Izvi zvinonyanya kukosha kumaindasitiri ezvipfuyo nehuku, uko kuve nechokwadi chekudya kwakakwana kuti hukure zvakanaka uye huve nehutano hwakanaka kwakakosha.
Nzvimbo idzi dzinoratidza kushandiswa kwakasiyana-siyana kweMTHF-Ca uye kushandiswa kwayo mumaindasitiri akasiyana-siyana kugadzirisa matambudziko ehutano ane chekuita nefolate uye zvinodiwa pakudya. Zvisinei, zvakakosha kutevedzera nhungamiro dzakakodzera dzemuyero uye kubvunza nyanzvi pakushandisa MTHF-Ca mune chero chigadzirwa kana musanganiswa.
Kuwanikwa kwezvinhu zvakagadzirwa:Maitiro acho anotanga nekutsvaga zvinhu zvemhando yepamusoro. Zvinhu zvikuru zvinodiwa pakugadzira MTHF-Ca i folic acid ne calcium salts.
Kushandurwa kwe folic acid kuita 5,10-Methylenetetrahydrofolate (5,10-MTHF):Folic acid inoshandurwa kuita 5,10-MTHF kuburikidza nemaitiro ekuderedza. Danho iri rinowanzo sanganisira kushandiswa kwezvinhu zvinoderedza zvakaita se sodium borohydride kana zvimwe zvinhu zvakakodzera.
Kushandurwa kwe5,10-MTHF kuita MTHF-Ca:Iyo 5,10-MTHF inosanganiswazve nemunyu wecalcium wakakodzera, wakadai secalcium hydroxide kana calcium carbonate, kuti igadzire Methyltetrahydrofolate Calcium (MTHF-Ca). Maitiro aya anosanganisira kusanganisa reactants uye kuabvumira kuti ashande mumamiriro ezvinhu akarongwa, kusanganisira tembiricha, pH, uye nguva yekuita.
Kucheneswa uye kusefa:Mushure mekuitwa kwechinhu ichi, mushonga weMTHF-Ca unoitwa nenzira dzekuchenesa dzakadai sekusefa, kupinza mvura mumhepo, kana dzimwe nzira dzekuparadzanisa tsvina nezvimwe zvinhu zvinogona kunge zvakaumbwa panguva yekuitwa kwechinhu ichi.
Kuomesa uye kuomesa:Mushonga weMTHF-Ca wakacheneswa unozogadziriswazve kubvisa hunyoro hwakawandisa uye kusimbisa chigadzirwa chekupedzisira. Izvi zvinogona kuitwa kuburikidza nenzira dzakadai sekuomesa nepfapfaidzo kana kuomesa nechando, zvichienderana nerudzi rwechigadzirwa chaunoda.
Kudzora kunaka uye kuyedzwa:Chigadzirwa chekupedzisira cheMTHF-Ca chinoongororwa zvakasimba kuti chive nechokwadi chekuti chakachena, chakasimba, uye chinotevedzera mitemo yemhando yakatarwa. Izvi zvinogona kusanganisira kuyedzwa kwetsvina, simba, nezvimwe zvinhu zvakakosha.
Kurongedza nekuchengetera:MTHF-Ca inoiswa mumidziyo yakakodzera, zvichiita kuti ionekwe zvakanaka uye ichengeterwe zvakanaka kuti irambe yakasimba uye yakachengeteka. Inowanzo chengetwa munzvimbo yakaoma, inotonhorera kure nezuva rakananga.
Kuchengeta: Chengeta munzvimbo inotonhorera, yakaoma, uye yakachena, Dzivirira kubva kuhunyoro nechiedza chakananga.
Pakeji Yakawanda: 25kg/dhiramu.
Nguva Yekutungamira: Mazuva manomwe mushure mekuraira kwako.
Hupenyu hweSherufu: Makore maviri.
Mhinduro: Magadzirirwo akagadzirwa anogonawo kuwanikwa.
20kg/bhegi 500kg/pallet
Kurongedza kwakasimbiswa
Kuchengetedzwa kwezvinhu
Ratidza
Pasi pe100kg, Mazuva 3-5
Basa repasuo nesuo riri nyore kutora zvinhu
Negungwa
Kupfuura 300kg, Mazuva Anosvika 30
Nyanzvi yekubvisa magwaro inodiwa pachiteshi chengarava kuenda kune chimwe chiteshi
Nemhepo
100kg-1000kg, Mazuva mashanu kusvika manomwe
Nyanzvi yekubvisa magwaro kubva kunhandare yendege kuenda kunhandare yendege inodiwa
Methyltetrahydrofolate Calcium yakachena (5-MTHF-Ca)ine chitupa cheISO, chitupa cheHALAL, uye chitupa cheKOSHER.
Musiyano uripo pakati pechizvarwa chechina chefolic acid (5-MTHF) nefolic acid yechinyakare uri muchimiro chemakemikari avo uye kuwanikwa kwavo mumuviri.
Maumbirwo emakemikari:Folic acid yechinyakare imhando yefolate yakagadzirwa uye inofanira kutorwa matanho akawanda ekuchinja muviri isati yashandiswa. Kune rumwe rutivi, folic acid yechizvarwa chechina, inozivikanwawo se5-MTHF kana Methyltetrahydrofolate, ndiyo mhando yefolate inoshanda uye inowanikwa muhupenyu isingade kushandurwa.
Kuwanikwa kwehupenyu:Folic acid yechinyakare inofanira kuchinjwa kuita chimiro chayo chinoshanda, 5-MTHF, kuburikidza nemaitiro ema enzyme mumuviri. Maitiro aya ekushandura anosiyana pakati pevanhu uye anogona kukanganiswa nekusiyana kwemajini kana zvimwe zvinhu. Kusiyana neizvi, 5-MTHF yatove muchimiro chayo chinoshanda, zvichiita kuti iwanikwe nyore nyore kuti itore uye ishandiswe nemasero.
Kunyudzwa uye kushandiswa:Kutorwa kwefolic acid yechinyakare kunoitika muura hudiki, uko kunoda kushandurwa kuita chimiro chinoshanda neenzyme dihydrofolate reductase (DHFR). Zvisinei, maitiro aya ekushandura haashande zvakanaka kune vamwe vanhu, zvichiita kuti bioavailability isashande zvakanyanya. 5-MTHF, sezvo iri chimiro chinoshanda, inonyudzwa nyore nyore uye inoshandiswa nemuviri, ichipfuura maitiro ekushandura. Izvi zvinoita kuti ive chimiro chinodiwa kune vanhu vane majini akasiyana kana mamiriro ezvinhu anokanganisa metabolism yefolate.
Kugwinya kwevamwe vanhu:Nekuda kwekusiyana kwekunwa uye kushandiswa, 5-MTHF inoonekwa seyakakodzera vanhu vane mamwe majini akasiyana, akadai seMTHFR gene mutations, izvo zvinogona kukanganisa kushandurwa kwefolic acid kuita chimiro chayo chinoshanda. Kune vanhu ava, kushandisa 5-MTHF zvakananga kunogona kuve nechokwadi chekuti folate yakawanda mumuviri uye kutsigira mabasa akasiyana-siyana ehupenyu.
Kuwedzera:Asidhi yefolic yechinyakare inowanikwa muzvikafu zvinovaka muviri, zvekudya zvakasimbiswa, uye zvekudya zvakagadzirwa, sezvo isinganyanyi kudhura kugadzira. Zvisinei, kune kuwanikwa kuri kuwedzera kwe5-MTHF supplements inopa chimiro chinoshanda zvakananga, izvo zvinogona kubatsira kune vanhu vane dambudziko rekushandura folic acid.
Migumisiro ye folic acid yechizvarwa chechina (5-MTHF) inowanzo kuve isingawanzoitiki uye iri nyore, asi zvakakosha kuziva nezvemigumisiro inogona kuitika:
Kurwara neallergy:Kufanana nechero mushonga unowedzerwa kana mishonga, zviratidzo zvekusawirirana zvinogona kuitika. Zviratidzo zvinogona kusanganisira mapundu, kuvaviwa, kuzvimba, dzungu, kana kuoma kufema. Kana ukaona chimwe chezviratidzo izvi, tsvaga rubatsiro rwechiremba nekukasika.
Matambudziko ekugaya chikafu:Vamwe vanhu vanogona kusangana nematambudziko emudumbu, akadai sekusvotwa, kuzvimba, gasi, kana manyoka. Zviratidzo izvi zvinowanzova zvenguva pfupi uye zvinopera muviri paunojaira kudya zvinowedzerwa.
Kudyidzana nemishonga:5-MTHF inogona kupindirana nemimwe mishonga, kusanganisira mishonga inoshandiswa kurapa kenza, mishonga inorwisa pfari, methotrexate, uye mimwe mishonga inorwisa mabhakitiriya. Zvakakosha kutaura nemupi wehutano hwako kana uri kutora mimwe mishonga kuti uve nechokwadi chekuti hapana mishonga inogona kupindirana.
Kuwanda kwemafuta kana kuwanda kwemafuta ane folate:Kunyange zvazvo zvisingawanzoitiki, kudya folate zvakanyanya (kusanganisira 5-MTHF) kunogona kukonzera kuwanda kwe folate muropa. Izvi zvinogona kuvharidzira zviratidzo zvekushaikwa kwevhitamini B12 uye kukanganisa kuongororwa nekurapwa kwemamwe matambudziko. Zvakakosha kutevedzera mwero unokurudzirwa uye kubvunza nyanzvi yehutano kuti ikubatsire.
Zvimwe zvinhu zvinofanira kufungwa nezvazvo:Vakadzi vane pamuviri kana avo vari kuronga kubata pamuviri vanofanira kutaura nevanopa hutano hwavo vasati vatora mishonga yakawanda ye5-MTHF, sezvo kudya zvakanyanya folate kunogona kuvharira zviratidzo zvekushaikwa kwevhitamini B12, iyo inokosha pakukura kwetsinga dzeuropi mumwana ari mudumbu.
Sezvinoita chero mishonga yekuwedzera kana yekuwedzera, zvakakosha kukurukura nezvekushandiswa kweFourth-generation folic acid (5-MTHF) nechiremba, kunyanya kana uine matambudziko ehutano kana kuti uri kutora mimwe mishonga. Vanogona kukupa mazano emunhu wega zvichienderana nezvaunoda uye kubatsira kutarisa chero migumisiro inogona kuitika.
Folic acid yechizvarwa chechina, inozivikanwawo se5-methyltetrahydrofolate (5-MTHF), imhando yefolate inoshanda mumuviri iyo inonyudzwa zviri nyore uye inoshandiswa nemuviri zvichienzaniswa nekuwedzera folic acid yechinyakare. Heano mamwe masongororo esainzi anotsigira kushanda kwayo:
Kuwedzera kwekuwanikwa kwemuviri:Zvakaratidzwa kuti 5-MTHF ine bioavailability yakakura kupfuura folic acid. Chidzidzo chakaburitswa muAmerican Journal of Clinical Nutrition chakaenzanisa bioavailability ye folic acid ne 5-MTHF mumadzimai ane hutano. Chakaona kuti 5-MTHF yaikurumidza kunyudzwa uye zvakaita kuti masero matsvuku eropa ave ne folate yakawanda.
Kuvandudzwa kwe folate:Zvidzidzo zvakawanda zvakaratidza kuti kuwedzerwa kwe5-MTHF kunogona kuwedzera huwandu hwefolate muropa. Muongororo yakarongwa nemaitiro akarongwa yakaburitswa muJournal of Nutrition, vaongorori vakaenzanisa mhedzisiro ye5-MTHF nefolic acid supplementation pahuwandu hwefolate muvakadzi vane hutano. Vakaona kuti 5-MTHF yaishanda zvakanyanya mukuwedzera huwandu hwefolate mumasero matsvuku eropa kupfuura folic acid.
Kuvandudzwa kwe folic acid metabolism:5-MTHF yakaratidzwa kuti inodarika matanho eenzyme anodiwa kuti folic acid ishande uye inobatanidzwa zvakananga mu metabolism yemasero efolic acid. Chidzidzo chakaburitswa muJournal of Nutrition and Metabolism chakaratidza kuti 5-MTHF supplementation inovandudza metabolism yemukati memasero efolate muvanhu vane kusiyana kwemajini mumaenzymes anobatanidzwa mukuita kuti folic acid ishande.
Kuderera kwemazinga e homocysteine:Kuwanda kwehomocysteine, amino acid muropa, kwakabatana nekuwedzera kwenjodzi yezvirwere zvemwoyo. Zvidzidzo zvakaratidza kuti kuwedzera kwe5-MTHF kunogona kuderedza zvinobudirira huwandu hwehomocysteine. Kuongorora kwakaburitswa muJournal of the American College of Nutrition kwakaongorora miedzo makumi maviri nemapfumbamwe yakarongwa uye kwakagumisa kuti kuwedzera kwe5-MTHF kwaishanda zvakanyanya kupfuura folic acid mukuderedza huwandu hwehomocysteine.
Zvakakosha kuziva kuti mhinduro dzemunhu mumwe nemumwe pakuwedzera mishonga inogona kusiyana, uye kushanda kwe5-MTHF kunogona kutsamira pazvinhu zvakaita sekusiyana kwemajini mumaenzymes e folate metabolism uye kudya kwakazara. Zvinokurudzirwa nguva dzose kubvunza chiremba kuti akupe mazano akakodzera maererano nekuwedzera mishonga uye kukurukura chero matambudziko ehutano kana mamiriro ezvinhu.
