Poda yeCepharanthine Yechisikigo Yakachena
Poda yeCepharanthine Yechisikigo Yakachenaimhando yeupfu ye cephalanthine, iyo inobva mumuti we Stephania cephalantha. I bisbenzylisoquinoline alkaloid yechisikigo uye yagara ichishandiswa mumishonga yeChinese neyeJapan nekuda kwehunhu hwayo hwemishonga, kusanganisira antioxidant, anti-inflammatory, immunomodulatory, antitumoral, uye antiviral activity.
Munyaya yeCOVID-19, cephalanthine yakaratidza kushanda kwakanaka pakurwisa COVID-19. Yakaratidza kudzivirira kukuru kweSARS-CoV-2, hutachiona hunokonzera COVID-19. Zviratidzo zveIC50 neIC90 zve cephalanthine pakurwisa SARS-CoV-2 ndezve 1.90 µM uye 4.46 µM, zvichiteerana.
Uyezve, cephalanthine yakaratidzwa kuti inodzosera kumashure kusasimba kwemishonga yakawanda kunokonzerwa neP-glycoprotein (P-gp) mumasero eK562 uye inowedzera kunzwa kwemishonga yekurwisa kenza mumamodheru embeva dzexenograft. Inoratidzawo mhedzisiro yekudzivirira paenzymes dze cytochrome P450 dzechiropa chemunhu dzakadai seCYP3A4, CYP2E1, uye CYP2C9.
Imhando yakasanganiswa yemusanganiswa uyu, iyo inogona kushandiswa pazvinangwa zvakasiyana-siyana, kusanganisira kutsvagisa, kugadzira mishonga, uye kugadzira mishonga.
Chimiro cheupfu chinoita kuti zvive nyore kubata, kuyera, uye kusanganisa cepharanthine, zvichiita kuti ive nyore kushandiswa mumabasa akasiyana. Inogona kushandiswa pakugadzira mishonga, mishonga yekuwedzera, kana mamwe maitiro anoshandisa hunhu hwekurapa hwe cepharanthine.
Poda yeCepharanthine Yechisikigo Yakachenainowanzo kuwanikwa kuburikidza nekubvisa nekuchenesa kuitira kuti pave nekuchena kwakanyanya uye mhando. Izvi zvinoita kuti upfu husave netsvina, tsvina, kana zvimwe zvinhu zvinogona kukanganisa kushanda kwayo kana kuchengetedzeka kwayo.
| Chinhu | Tsanangudzo | Mhedzisiro Yebvunzo |
| Chitarisiko | Upfu huchena, hwema hwakasiyana-siyana, hunonyatso shanda zvakanaka | Zvinoenderana |
| Kuzivikanwa | TLC: Mhinduro yakajairika uye mhinduro yekuyedza panzvimbo imwe chete, RF | Zvinoenderana |
| Kuyedza (Hwaro Hwakaoma) | 98.0%--102.0% | 98.1% |
| Optical chaiyo | -2.4°~ -2.8° | -2.71° |
| PH | 4.5~7.0 | 5.3 |
| Simbi Dzinorema (SePb) | ≤10ppm | <10ppm |
| As | ≤1ppm | Hazvina Kuonekwa |
| Pb | ≤0.5ppm | Hazvina Kuonekwa |
| Cd | ≤1ppm | Hazvina Kuonekwa |
| Hg | ≤0.1ppm | Hazvina Kuonekwa |
| Zvinhu zvine chekuita nazvo | Nzvimbo yacho haina kukura kupfuura yakajairwa nzvimbo yekugadzirisa | Hapana nzvimbo |
| Chinonyungudutsa chakasara | <0.5% | Zvinotevedzera |
| Mvura Yakawanda | <2% | 0.18% |
(1) Pure Natural Cepharanthine Powder inobva muzvinhu zvakasikwa, kunyanya chirimwa cheStephania cepharantha Hayata.
(2) Imhando yakabatana ye cephalanthine, zvichiita kuti zvive nyore kubata, kuyera, uye kusanganisa.
(3) Upfu hwacho hwakakodzera zvinangwa zvakasiyana-siyana, zvinosanganisira kutsvagisa, kugadzira mishonga, uye kugadzira mushonga.
(4) Inobviswa uye inocheneswa kuitira kuti ive nechokwadi chekuti yakachena uye ine mhando, isina tsvina kana zvinhu zvinosvibisa.
(5) Inogona kushandiswa kugadzira mishonga, mishonga yekuwedzera, kana mamwe maitiro anoshandisa kurapa kwe cephalanthine.
(1) Pure Natural Cepharanthine Powder yakaratidzwa kuti ine simba guru rekuchengetedza ma antioxidants, ichibvisa ma free radicals uye ichideredza oxidative stress.
(2) Inoratidza simba rekudzivirira kuzvimba, izvo zvinogona kubatsira kuderedza zviratidzo zvine chekuita nematambudziko ekuzvimba.
(3) Cepharanthine yakaongororwa nekuda kwesimba rayo rekurwisa utachiona, ichiratidza kushanda kwayo pakurwisa marudzi akasiyana-siyana emabhakitiriya nefungus.
(4) Inogona kunge iine hunhu hwekurwisa mavhairasi uye yakaongororwa kuti inogona kushanda sei kurwisa mamwe mavhairasi.
(5) Cepharanthine yakawanikwa iine simba rekugadzirisa masoja emuviri, zvichigona kuwedzera simba remasoja emuviri.
(6) Ongororo dzinoratidza kuti inogona kunge iine simba rekudzivirira kenza, zvichidzivisa kukura nekupararira kwemasero ekenza mumhando dzakasiyana dzekenza.
(7) Yakaongororwa kuti ione kana paine zvayakanakira pakurapa chirwere chemwoyo, zvakaita sekuvandudza kuyerera kweropa uye kutsigira hutano hwemwoyo.
(8) Cepharantine inogona kudzivirira tsinga dzemuviri, zvichigona kupa rutsigiro kumatambudziko etsinga.
Inoratidza tarisiro mune zvekurapa ganda, inogona kunge iine hunhu hwekudzivirira ganda uye kuporesa maronda.
(1) Indasitiri yemishonga
(2) Zvinovaka muviri uye zvekudya zvinovaka muviri
(3) Zvizoro uye kuchengetedza ganda
(4) Mishonga yechivanhu
(5) Tsvagiridzo nekuvandudza
(1) Kurima zvirimwa:Zvirimwa zveStephania cepharantha, zvinorimwa munzvimbo dzakakodzera kurima.
(2) Kukohwa:Zvirimwa zvakakura zvinosarudzwa nemaoko kuti zvive nechokwadi chekuti zvine mhando.
(3) Kuomesa:Zvirimwa zvakakohwewa zvinoomeswa uchishandisa nzira dzechinyakare kana nzira dzemazuva ano dzekubvisa hunyoro.
(4) Kubvisa:Zvirimwa zvakaomeswa zvinokuyiwa kuita upfu hwakatsetseka uye zvinotorwa uchishandisa zvinonyungudutsa zvakaita se ethanol kana mvura.
(5) Kusefa:Chinobviswa chinoseferwa kuti chibvise tsvina uye chiwane mhinduro yakajeka.
(6) Kuisa pfungwa pachinhu chimwe nechimwe:Filtrate inosanganiswa kubvisa solvent yakawandisa uye kuwedzera huwandu hweCepharanthine.
(7) Kucheneswa:Chinhu chakaomeswa chinozopedzisira chacheneswa zvakanyanya se chromatography kana crystallization kuti pave neCepharanthine yakachena.
(8) Kuomesa:Cepharanthine yakacheneswa inoomeswa kuti ibvise hunyoro hwasara.
(9) Kugadzira upfu:Cepharanthine yakaomeswa inogayiwa kuita upfu hwakatsetseka.
(10) Kudzora mhando:Upfu uhwu hunoongororwa zvakasimba kuti huve nechokwadi chekuti hunosangana nezvinodiwa zvehunhu hwekuchena, simba, uye kuchengetedzeka.
(11) Kurongedza:Chigadzirwa chekupedzisira chinoiswa mumidziyo isingapindi mhepo kuti chirambe chakanaka uye chigare kwenguva refu.
(12) Kuchengetera:Upfu hweCepharanthine hwakaputirwa hunochengetwa mumamiriro ezvinhu akakodzera kuti hurambe hwakagadzikana uye huchishanda zvakanaka.
Cherechedza: Maitiro chaiwo ekugadzira anogona kusiyana zvichienderana nemugadziri uye zvinodiwa.
Kuchengeta: Chengeta munzvimbo inotonhorera, yakaoma, uye yakachena, Dzivirira kubva kuhunyoro nechiedza chakananga.
Pakeji Yakawanda: 25kg/dhiramu.
Nguva Yekutungamira: Mazuva manomwe mushure mekuraira kwako.
Hupenyu hweSherufu: Makore maviri.
Mhinduro: Magadzirirwo akagadzirwa anogonawo kuwanikwa.
20kg/bhegi 500kg/pallet
Kurongedza kwakasimbiswa
Kuchengetedzwa kwezvinhu
Ratidza
Pasi pe100kg, Mazuva 3-5
Basa repasuo nesuo riri nyore kutora zvinhu
Negungwa
Kupfuura 300kg, Mazuva Anosvika 30
Nyanzvi yekubvisa magwaro inodiwa pachiteshi chengarava kuenda kune chimwe chiteshi
Nemhepo
100kg-1000kg, Mazuva mashanu kusvika manomwe
Nyanzvi yekubvisa magwaro kubva kunhandare yendege kuenda kunhandare yendege inodiwa
Poda yeCepharanthine Yechisikigo Yakachenaine chitupa cheISO, chitupa cheHALAL, uye chitupa cheKOSHER.
Migumisiro yePure Natural Cepharanthine Powder inogona kusiyana kubva pamunhu kuenda kune mumwe uye inogona kusaonekwa nemunhu wese. Mimwe migumisiro inogona kuitika yakataurwa inosanganisira:
Matambudziko eMudumbu:Vamwe vanhu vanogona kusangana nematambudziko emudumbu, akadai sekuda kurutsa, kurwadziwa mudumbu, manyoka, kana kuvimbiwa.
Kusawirirana:Muzviitiko zvisingawanzoitiki, chirwere chinogona kuitika, zvichikonzera zviratidzo zvakaita semapundu paganda, kuvaviwa, kuzvimba, kana kuoma kufema. Kana ukasangana nechirwere chekusawirirana nemishonga, rega kushandisa mushonga wacho wobva watsvaga rubatsiro rwechiremba nekukasika.
Kumanikidzwa kweropa uye mwero wemwoyo:Cepharanthine inogona kukanganisa BP uye kurova kwemoyo. Vanhu vane matambudziko emwoyo kana avo vari kutora mishonga yekuderedza BP vanofanira kungwarira uye kubvunza nyanzvi yehutano vasati vashandisa Cepharanthine.
Kudyidzana Nemishonga:Cepharanthine inogona kupindirana nemimwe mishonga, yakadai semishonga inorwisa ropa kupwanya kana mishonga inorwisa maplatelet. Kupindirana uku kunogona kukanganisa kuumbwa kweropa kana kuwedzera njodzi yekubuda ropa. Zvakakosha kuzivisa nyanzvi yehutano nezvemishonga yese yauri kutora usati washandisa Cepharanthine.
Mimwe Migumisiro Inogona Kuitika:Kunyange hazvo paine zvidzidzo zvishoma pamusoro pemigumisiro chaiyo yeCepharanthine, vamwe vanoshandisa mushonga uyu vakataura kuti vakambosangana nematambudziko ekurara, dzungu, musoro, kana kuchinja kwechido chekudya.
Zvakakosha kuziva kuti migumisiro yakaipa iri pamusoro apa haina kukwana, uye zvinoitika kumunhu mumwe nemumwe zvinogona kusiyana. Kana ukasangana nemhedzisiro inonetsa kana inoramba iripo paunenge uchitora Cepharanthine, zvakakosha kutsvaga rubatsiro rwechiremba uye kubvunza nyanzvi yehutano.
