Upfu hweSinomenine Hydrochloride
Sinomenine Hydrochloride ikemikari inobva mumuti weSinomenium acutum, unowanikwa kuEast Asia. I alkaloid yagara ichishandiswa mukurapa kwechiChinese nekuda kwesimba rayo rekudzivirira kuzvimba uye marwadzo. Munyu we hydrochloride unowedzera kunyungudika kwemushonga uye kugadzikana, zvichiita kuti uve wakakodzera kushandiswa mumishonga.
Sinomenine Hydrochloride yakaongororwa nekuda kwemhedzisiro yayo yekurapa zvirwere zvakaita serheumatoid arthritis, nekuda kwekugona kwayo kugadzirisa masoja emuviri nekuderedza kuzvimba. Inoshanda nekudzivisa kugadzirwa kwema cytokines anokonzera kuzvimba uye zvimwe zvinobatanidzwa mukupindura kwekuzvimba.
Pamusoro pemigumisiro yayo yekudzivirira kuzvimba uye marwadzo, Sinomenine Hydrochloride yakaratidzawo kugona kwayo mukudzivirira tsinga, kurwisa fibrosis, uye kurwisa bundu muzvidzidzo zvakasiyana-siyana zve preclinical.
Zita repamutemo: (9a,13a,14a)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-one, monohydrochloride
Nhamba yeCAS: 6080-33-7
Mazwi akafanana：Cucoline NSC 76021
Fomura yeMolecular： C19H23NO4 • HCl
Kurema kwefomura: 365.9
Kuchena: ≥98% A crystalline solid
Kunyungudika (Dzidza nezve Kusiyana kweKunyungudika)
DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 5 mg/ml
PBS (pH 7.2): 5 mg/ml
Mabviro: Chirimwa/Sinomenium acutum
Ruzivo rwekutumira & Kuchengeta:
Kuchengetera -20°C
Kutumira: Tembiricha Yekamuri
Kugadzikana: ≥ makore 4
| Chinhu | Tsanangudzo | Mhedzisiro |
| Kuyedza (HPLC) | 98.0% | 98.12% |
| Chitarisiko | upfu chena | Zvinotevedzera |
| Saizi yeChidimbu | 98% kusvika 80mesh | Zvinotevedzera |
| Kunhuhwirira | Hunhu | Zvinotevedzera |
| Ravira | Hunhu | Zvinotevedzera |
| Hunhu hwemuviri | ||
| Kurasikirwa Nekuomesa | ≤0.5% | 0.38% |
| Dota | ≤0.5% | 0.46% |
| Simbi dzinorema | ||
| Simbi dzinorema (sePb) | Mitemo yeUSP (<10ppm) | <10ppm |
| Arsenic (Se) | ≤2ppm | 0.78ppm |
| Mutobvu (Pb) | ≤2ppm | 1.13ppm |
| Cadmium(Cd) | ≤lpm | 0.36ppm |
| Mercary(Hg) | ≤0.1ppm | 0.01ppm |
| Zvakasara zveMishonga Yezvipembenene | Hazvina kuonekwa | Hazvina kuonekwa |
| Kuverengwa Kwemaplate | NMT 10000cfu/g | 680 cfu/g |
| Mbiriso Yese & Mould | NMT 100cfu/g | 87 cfu/g |
| E.Coli | NMT 30cfu/g | 10 cfu/g |
| Salmonella | Zvakaipa | Zvakaipa |
| Mhedziso | Zvinoenderana neBhizinesi Standard | |
Migumisiro mikuru yeSinomenine Hydrochloride inosanganisira:
(1) Kurwisa kuzvimba: Kunoderedza kuzvimba.
(2) Mushonga unonyaradza marwadzo: Unopa zororo rekurwadziwa.
(3) Inodzvinyirira masoja emuviri: Inoderedza mashandiro emasoja emuviri.
(4) Inorwisa rheumatoid arthritis: Inorapa rheumatoid arthritis.
(5) Kudzivirira tsinga dzeuropi: Kunodzivirira masero etsinga kubva mukukuvadzwa.
(6) Anti-fibrotic: Inodzivirira kana kuderedza fibrosis yetishu.
Sinomenine Hydrochloride inonyanya kushandiswa munzvimbo dzinotevera:
(1) Rheumatology: Kurapa rheumatoid arthritis.
(2) Kudzora Marwadzo: Kuderedza marwadzo asingaperi.
(3) Kurwisa kuzvimba: Kuderedza kuzvimba.
(4) Kuchinja kwesimba remuviri: Kuchinja kwesimba remuviri rekudzivirira muviri.
(5) Kudzivirira tsinga dzeuropi: Kunogona kushandiswa mukurapa tsinga dzeuropi.
Maitiro ekugadzira Sinomenine Hydrochloride Powder anogona kupfupikiswa seizvi:
Kugadzirira Mishonga:Kuchenesa nekuomesa chirimwa chisina kubikwa.
Kubvisa:Kushandisa zvinonyungudutsa zvakaita se ethanol kubvisa sinomenine kubva mumiti.
Kuisa pfungwa pachinhu chimwe:Kubvisa chinhu chinonyungudutsa kuti chisanganise huwandu hwesinomenine.
Alkalization:Kugadzirisa pH kuti ishandure sinomenine kuita munyu wayo.
Kubviswa kwemvura-mvura:Kuchenesa nezvinonyungudutsa zvakaita seanisole kana 1-heptanol.
Kugeza:Kushambidzwa nemvura kubvisa tsvina uye zvisaririra zve solvent.
Kuisa acid muropa:Kuderedza pH kuti sinomenine hydrochloride iite seyakakura.
Kugadzirwa kwekristaro:Kugadzira makristaro e sinomenine hydrochloride.
Kuparadzana:Kusefa kana kuparadzanisa makristaro kubva mumushonga.
Kuomesa:Kubvisa hunyoro hwasara kubva mumakristaro.
Kugaya:Kukuya makristaro akaomeswa kuita upfu hwakatsetseka.
Kuvhara:Kuve nechokwadi chekupararira kwehukuru hwezvimedu zvakaenzana.
Kudzora Hunhu:Kuyedzwa kwekuchena, kutarisisa, uye mwero wezvinhu zvipenyu.
Kurongedza:Kurongedza kwakachengeteka uye kusina utachiona kuti zvigoverwe.
Kuchengeta: Chengeta munzvimbo inotonhorera, yakaoma, uye yakachena, Dzivirira kubva kuhunyoro nechiedza chakananga.
Pakeji Yakawanda: 25kg/dhiramu.
Nguva Yekutungamira: Mazuva manomwe mushure mekuraira kwako.
Hupenyu hweSherufu: Makore maviri.
Mhinduro: Magadzirirwo akagadzirwa anogonawo kuwanikwa.
Ratidza
Pasi pe100kg, Mazuva 3-5
Basa repasuo nesuo riri nyore kutora zvinhu
Negungwa
Kupfuura 300kg, Mazuva Anosvika 30
Nyanzvi yekubvisa magwaro inodiwa pachiteshi chengarava kuenda kune chimwe chiteshi
Nemhepo
100kg-1000kg, Mazuva mashanu kusvika manomwe
Nyanzvi yekubvisa magwaro kubva kunhandare yendege kuenda kunhandare yendege inodiwa
Bioway Organic yawana zvitupa zveUSDA neEU organic, BRC, ISO, HALAL, KOSHER, uye HACCP.
